CBD vs. THC explained

Cannabidiol (CBD) and tetrahydrocannabinol (THC) are two cannabinoids with an almost identical molecular structure, but with very different effects on the mind.

Cannabinoids interact with receptors in the body’s endocannabinoid system - CB1 receptors are abundant in the brain, while CB2 receptors are found throughout the central nervous and immune systems.

CB1 receptors are activated by anandamide, a neurotransmitter naturally produced by the body that directly relates to things like pleasure, memory, focus and appetite.

Because of THC’s similarity in structure to anandamide, it fits perfectly into the receptor and mimics the ‘high’ that large quantities of anandamide produce.

CBD, however, is very different in structure to anandamide and THC, and so it does not bind as well to these receptors. CBD affects mind and mood in a very different way, inhibiting the FAAH enzyme responsible for breaking down anandamide in the body.

More anandamide being built up means greater mood boosting and relief from anxiety, but without the elevated feeling that THC often provides.